Insemination with donor sperm

What is an insemination with donor sperm?

It is the indicated treatment for patients who, for different reasons, do not have available sperm cells capable of producing normal embryos. It consists of an intrauterine insemination with donor sperm. Donor sperm is always frozen and can only be used if, after 6 months, the blood analysis of the donor still confirms a negative result for infectious diseases.

How is the insemination with donor sperm performed?

Firstly, all necessary interviews and tests are carried out and the physical features, the blood group and Rh factor of the patients are taken note of to match them with a suitable donor.

At out centre, we only perform intrauterine inseminations, which take place having previously capacitated the sperm in the laboratory. During the freezing and thawing processes the sperm can lose mobility despite being of very good quality, and therefore results are better if the sperm is capacitated after thawing.

How do we select sperm donors?Egg donor

At Institut Marquès we have our own Premium Sperm Bank and vast experience in donor selection. The donor is personally chosen by the doctor to guarantee the most suitable for each patient. The matching process takes into account both the blood group and the RH as well as the physical features of future parents (eye, hair and skin color, etc …). Donors undergo a thorough sociological and psychological assessment and a full medical check-up and blood works, including the study of their karyotype, several tests to rule out infectious diseases and specific tests to rule out the most frequent mutations in the European population. They also perform blood tests that are repeated periodically to detect sexually transmitted diseases. Moreover, the family medical history is reviewed to discard possible genetic illnesses. Finally, they undergo tests to rule out any chromosomal abnormalities in the ejaculated sample (FISH in sperm) and to detect the 50 most common cystic fibrosis mutations. According to Spanish legislation, semen donors must be between 18 and 50 years old.

Can donor inseminations be performed by placing the sperm in the cervix?

Inseminations can be carried out by collecting the sperm in a recipient and placing it in the cervix, but the results are not good. Institut Marqués performs only intrauterine inseminations (injecting the sperm in the uterus) for more than 10 years.

Do I need to sign a consent form for sperm donation?

Yes. This document mentions that the insemination will be carried out with sperm from a donor. The legal aspects of using sperm donation are also explained.

Are the success rates high?

The pregnancy chances depend mainly on the age of the patient and the number of follicles that develop in a cycle. With ovarian stimulation and intrauterine insemination the pregnancy chances per cycle are 20-25%. After four cycles, approximately 70% of the patients have achieved a pregnancy.